| | Adaias Oliveira Matos | College of Dentistry | Prosthodontics | Associate Professor |
| | Angela Orr | College of Health Professions | Audiology & Speech Pathology - Hearing & Speech Center | Assistant Professor |
| | Mary Owens | College of Medicine - Memphis | Surgery - General Surgery | Assistant Professor |
| | Chelsea Olson | College of Medicine - Memphis | Surgery - Surgical Oncology | Assistant Professor |
| | Dustin Osborne | College of Medicine - Knoxville | Knox Radiology | Professor |
| | Henry Okafor | College of Medicine - Chattanooga | Chat Urology | Assistant Professor |
| | Kyle Osborn | College of Medicine - Knoxville | Knox Family Medicine | Assistant Professor |
| | Lucianne Olewinski | College of Medicine - Knoxville | Knox Family Medicine | Associate Professor |
| | Marilyn Owens | College of Health Professions | Audiology & Speech Pathology - Hearing & Speech Center | Assistant Professor |
| | Peggy O'Cain | College of Medicine - Memphis | Family Medicine - WestTn Family Practice-Memphis | Assistant Professor |
| | Shelley Ost | College of Medicine - Memphis | Medicine - Med General Internal Medicine | Associate Professor |
| | Teresa O'Daniel | College of Dentistry | Dental Hygiene | Assistant Professor |
| | Twisha Oza | College of Medicine - Memphis | Pathology | Associate Professor |
| | Ugochi Ogu | College of Medicine - Memphis | Medicine - Med Hematology & Oncology | Associate Professor |
| | Yoshitsugu Obi Obi | College of Medicine - Memphis | Medicine - Med Nephrology | Associate Professor |
