Clinical Trials
Optimizing Treatment of Older adults with Hypertension: A Net Benefit Analysis of Falls Injury vs Cardiovascular (University of Michigan Subcontract USHPS AG-047178) PI: Min; UT PI: William Cushman
The study shows how a national healthcare system SSE for Study # 17530 m, the Veterans Health Administration (VHA), delivers aggressive hypertension care (AHC) and whether AHC results in net benefit or harm due to cardiovascular events and severe fall-related injury.
Vitamin D and Type 2 Diabetes (Tufts Medical Ctr Subcont USHPS U01DK98245 PI: Pittas; UT PI: Karen Johnson
The overall objective of the study is to test whether optimizing vitamin D status with vitamin D3 supplementation is associated with reduction in the rate of progression from pre-diabetes to diabetes.
Action for health in Diabetes Extension Study Research Project (USPHS U01DK057078) PI: Karen Johnson
Look AHEAD is a multicenter, randomized clinical trial to examine the effects of a
lifestyle intervention designed to achieve and maintain weight loss over the long
term through decreased caloric intake and exercise and to determine the long term
effects of weight loss on physical functioning, aging, and mortality.
The Effect of a Microprocessor Prosthetic Foot on Function and Quality of Life in
Transtibial Amputees Who are Limited Community Ambulators (VALOR) (Army Grant W81XWH15-1-0470) PI: Richey
This project will evaluate the efficacy of a using a microprocessor prosthetic foot
on functional performance, decreasing the risk of falls and improving quality of life
in transtibial amputees. The project will utilize a patient-centered approach for
veterans who function at a limited ambulatory level.
The effect of a powered ankle foot orthosis (PAFO) on function, safety & quality of
life in military service members and veterans who wear a prescribed orthosis (Army Grant W81XWH17-1-0451) PI: Richey
This project will evaluate the efficacy of a using a powered ankle foot orthosis (PAFO),
that assists with toe clearance and provides push-off power when taking a step, on
functional performance, decreasing the risk of falls and improving quality of life,
in military service members and veterans who walk with a prescribed AFO.
ASPirin in Reducing Events in the Elderly ASPREE (Minneapolis Medical Research Foundation Subcont USHPS U01 AG029824) PI: Catherine
Womack
The study is examining whether the potential benefits of low dose aspirin (particularly
the prevention of heart disease, stroke, certain cancers and dementia) outweigh the
risks (particularly severe gastrointestinal bleeding and hemorrhagic stroke) in this
age group. Participants were eligible for the trial if they did not have a current
clinical indication for (i.e. overt cardiovascular disease) or contraindication to
(i.e. allergy or increased risk of bleeding) aspirin, did not have dementia, disability,
low hemoglobin levels, or a condition that was likely to be fatal within five years
of enrollment and were capable of providing informed consent.