College of Pharmacy Research
The researchers and scientists at the UT Health Science Center College of Pharmacy address critical healthcare challenges through drug discovery, preclinical and clinical development through drug utilization, outcome research, and clinical research targeted at the refinement of applied pharmacotherapy. Thus, the college possesses comprehensive expertise to address research questions throughout a drug's life cycle, from its early stages as a potential candidate to its clinical use in patient subpopulations.
Specific areas of expertise focus on pediatrics, infectious diseases, cancer chemotherapy, and cardiovascular and metabolic diseases.
A diverse and well-balanced portfolio of funding sources from federal and state agencies, foundations, and commercial entities complements the College’s wide range of research activities.
Pharmacy Faculty Research Interests
Director of PhD Program
Associate Professor
Department of Pharmaceutical Sciences
- Oral and transdermal drug delivery
- Drug solubility enhancement
- Drug stability enhancement
- Drug permeability enhancement
- Pediatric drug delivery
Associate Professor
Department of Pharmaceutical Sciences
- Proteomics
- Biomarker and drug target discovery
- Retinal diseases
- Oxidative stress
- Biological mass spectrometry
Assistant Professor
Department of Pharmaceutical Sciences
- Traumatic brain injury (TBI)
- Cardiovascular disease
- Calcium signaling
- Genetically-encoded calcium indicators
- High-resolution 4D microscopy
Assistant Professor
Department of Clinical Pharmacy and Translational Science
- HIV
- Cellular reservoirs of HIV
- Drug efflux transporters
- Macrophages
- P-glycoprotein
Associate Professor
Department of Clinical Pharmacy and Translational Science
- Fungal pathogenesis
- Antifungal drug resistance
- Antifungal drug efficacy
- CRISPR/Cas9-based gene editing
- Fungal genetics
Assistant Professor
Department of Pharmaceutical Sciences
- Alcoholic liver disease
- Obesity/nonalcoholic fatty liver disease
- Nuclear receptors
- Type 2 diabetes
- Gut microbiome
Assistant Professor
Department of Pharmaceutical Sciences
- Infectious disease
- Antibacterial design
- Structural biology
- Computer-aided drug design
- Protein biochemistry
Assistant Professor
Department of Clinical Pharmacy and Translational Science
- Fungal pathogenesis
- Fungal immunology
- Innate immunity
- Cryptococcosis
- Pulmonary infections
Professor
Department of Pharmaceutical Sciences
- Prostaglandin signaling
- G protein-coupled receptors
- Neuroinflammation
- Blood-brain barrier
- Chemical neuroscience
Assistant Dean for Scholarly Integration and Collaboration
Professor
Department of Pharmaceutical Sciences
- HIV
- Substance abuse
- Cytochrome P450
- Extracellular vesicles
- Oxidative stress
Professor
Department of Pharmaceutical Sciences
- Natural products
- Drug discovery
- Organic chemistry
- Antibacterial
- Anti-cancer
Assistant Professor
Department of Pharmaceutical Sciences
- Cardiovascular disease
- Obesity/Type 2 diabetes
- Cell signaling
- Protein trafficking
- Epigenetics
Director of UTHSC COP Drug Discovery Center
Distinguished Professor
Department of Pharmaceutical Sciences
- Small molecule drug discovery
- Medicinal chemistry
- Cancer biology
- Computer-aided drug design
- Organic synthesis
Associate Dean, Graduate Programs and Research
Professor and Chair
Department of Pharmaceutical Sciences
- Pharmacometrics
- Pharmacokinetic/Pharmacodynamic modeling
- Anti-infective drug discovery and development
- Therapeutic protein PK/PD
- Pediatric clinical pharmacology
Professor Emeritus
Department of Pharmaceutical Sciences
- Medicinal chemistry
- Organic synthesis of small drug molecules
- Tubulin inhibitors for cancer treatment
- Androgen agonists and antagonists
- Drugs for glioblastoma and other brain cancers
Professor
Department of Pharmaceutical Sciences
- Development of novel agonists and inverse agonists of cannabinoid receptor 2
- Signaling pathways of cannabinoid receptor 1 in the central nervous system
- Molecular modeling
- Synthetic chemistry
- Pharmacological evaluation of new compounds
Associate Professor
Department of Clinical Pharmacy and Translational Science
- Infectious fungi
- Mechanisms of fungal pathogenesis
- Antifungal discovery
- Antifungal drug resistance
Associate Professor
Department of Pharmaceutical Sciences
- Acute kidney injury
- Epithelial cell regeneration
- G-protein regulators
- SIgnal transduction
- Lentiviral vectors
Associate Professor
Department of Clinical Pharmacy and Translational Science
- Mucosal candidiasis
- Innate immunity and inflammation
- Polymicrobial interactions
- Microbial genetics
- Drug repurposing
Associate Professor
Department of Pharmaceutical Sciences
- Inflammation (mucosal and bladder)
- Obesity and metabolic disease
- Alternative medicine
- Autoimmune diseases
- Innate immunity
Assistant Professor
Department of Pharmaceutical Sciences
- Vascular calcification
- Cardiovascular disease
- Atherosclerosis
- Lymphanogiogenesis
- Cholesterol efflux
Professor
Department of Pharmaceutical Sciences
- Targeted drug discovery
- Immunotherapy
- Cancer biology and therapeutics
- PK/PD
- Nanomaterials
Associate Professor
Department of Pharmaceutical Sciences
- Structure-based drug design and development
- Cancer therapeutic development
- Immune-mediated diseases and disorders
- Targeting RNA splicing factors in cancers
- Computational modeling and simulation