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College of Pharmacy Research

At UT Health Science Center College of Pharmacy, our researchers and scientists work tirelessly to tackle critical healthcare issues through drug discovery, development, and research to enhance pharmacotherapy.

The College has extensive expertise to investigate research questions across the entire life cycle of a drug, from its early development as a potential candidate to its clinical application in specific patient subgroups. Key areas of focus include pediatrics, infectious diseases, cancer chemotherapy, as well as cardiovascular and metabolic diseases.

The College benefits from a diverse and well-rounded portfolio of funding sources, including support from federal and state agencies, foundations, and commercial entities, which complement its wide array of research endeavors.

Ranked #19 in national PharmD programs & #1 in Tennessee
#13 among schools of pharmacy in NIH research funding
$17.6 million in total research dollars in 2023
259 Faculty Publications in 2023
Faculty Research InterestsResearch Resources and Analytical Facility

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Key Areas of Research

Therapeutic Targets and Molecular Mechanisms of Disease

Research in this area aims to identify and validate new drug targets (endogenous proteins) relevant to treating diseases such as cancer, neurological conditions, metabolic disorders and infectious diseases using biochemical and biological approaches.

Faculty in Therapeutic Targets and Molecular Mechanisms of Disease

Drug Discovery and Development

Research in this area includes the design, synthesis, and biological evaluation of new chemical entity with potential use in treating diseases such as cancer, infections, disorders of the endocrine, cardiovascular, central, and peripheral nervous systems.

Faculty in Drug Discovery and Development

Pharmacometrics

Research in this area includes the quantitative assessment of drug disposition (pharmacokinetics), effects (pharmacodynamics) using mathematical models based on biology, physiology, pharmacology and different disease states.

Faculty in Pharmacometrics

Drug Delivery and Targeting

Research in this area includes the design and evaluation of novel and translational drug delivery systems which can lead to targeted delivery systems to different organs in the body, to enhance the in vivo stability and permeability of novel molecules with reduced toxicity.

Faculty in Drug Delivery and Targeting

Clinical Pharmacy and Translational Science

Translational science describes the process of turning observations identified in the laboratory, clinic, and community into interventions that improve the health of individuals and the public — from diagnostics and therapeutics to medications and behavioral changes.
 
Clinical pharmacy practice embraces the philosophy of pharmacists providing direct patient care while utilizing specialized therapeutic knowledge, experience, and judgment to ensure optimal patient outcomes.

Health Outcomes and Policy Research

Health Outcomes and Policy Research focuses on the population-level impact of health policies, health systems, and health interventions on health outcomes, particularly regarding therapeutic outcomes from medication utilization. This interdisciplinary field examines the access, effectiveness, and economics of healthcare interventions and policies. Examples of critical outcomes of our research include access to health disparities, clinical outcomes, and economic outcomes. By examining the interplay between health outcomes and policy research, we guide decision-makers, enhance health outcomes, and optimize resource investment.

Research Centers and Institutes

Dec 5, 2024