Skip to content

Other ways to search: Events Calendar | UTHSC News

TJ Hollingsworth, PhD

Assistant Professor
Department of Ophthalmology
Department of Anatomy and Neurobiology

University of Tennessee Health Science Center
Hamilton Eye Institute
930 Madison Ave, Ste 737
Memphis, TN 38163
Phone: 901.448.7830
Fax: 901.448.5028


  • PhD Institution: University of Alabama at Birmingham; Vision Science Graduate Program; Department of Optometry
  • Postdoctoral: University of Oklahoma Health Science Center; Department of Physiology
  • Postdoctoral: University of Tennessee Health Science Center; Department of Ophthalmology, Hamilton Eye Institute


Research Interests

Molecular mechanisms of disease pathogenesis underlying neurodegenerative diseases of the retina including retinitis pigmentosa, Leber congenital amaurosis, age-related macular degeneration, and glaucoma; gene therapy; the role of inflammation in retinal disease pathogenesis; small molecular therapies for treating retinal disease.

Representative Publications

  •  Rho, J., Percelay, P., Pilkinton, S., Hollingsworth, T.J., Jablonski, M. M. An Overview of Age-Related Macular Degeneration: Clinical, Pre-Clinical Animal Models and Bidirectional Translation. Animal Models in Medicine and Biology. London, SW7 2QJ: IntechOpen 2021.
  • Pilkinton, S., Hollingsworth, T.J., Jerkins, B.M., Jablonski, M.M. An Overview of Glaucoma: Bidirectional Translation between Humans and Pre-Clinical Animal Models. Animal Models in Medicine and Biology. London, SW7 2QJ: IntechOpen 2021.
  • Jordan, KE, Jablonski, MM, and Hollingsworth, TJ. Inflammation in the pathogenesis of progressive retinal dystrophies. Journal of Ophthalmic Research and Vision Care. 2021. 
  • Hollingsworth TJ, Hubbard MG, Levi HJ, White W, Wang X, Simpson R, Jablonski MM, Gross AK. Proinflammatory Pathways Are Activated in the Human Q344X Rhodopsin Knock-In Mouse Model of Retinitis Pigmentosa. Biomolecules. 2021 Aug 6;11(8). doi: 10.3390/biom11081163. PubMed PMID: 34439829; PubMed Central PMCID: PMC8393353.
  • Hussain SM, Kansal RG, Alvarez MA, Hollingsworth TJ, Elahi A, Miranda-Carboni G, Hendrick LE, Pingili AK, Albritton LM, Dickson PV, Deneve JL, Yakoub D, Hayes DN, Kurosu M, Shibata D, Makowski L, Glazer ES. Role of TGF-β in pancreatic ductal adenocarcinoma progression and PD-L1 expression.Cell Oncol (Dordr). 2021 Jun;44(3):673-687. doi: 10.1007/s13402-021-00594-0. Epub 2021 Mar 10. PubMed PMID: 33694102.
  • Calame DJ, Xiao J, Khan MM, Hollingsworth TJ, Xue Y, Person AL, LeDoux MS. Presynaptic PRRT2 Deficiency Causes Cerebellar Dysfunction and Paroxysmal Kinesigenic Dyskinesia. Neuroscience.2020 Nov 10;448:272-286. doi: 10.1016/j.neuroscience.2020.08.034. Epub 2020 Sep 4. PubMed PMID: 32891704.
  • Ibrahim MM, Maria DN, Wang X, Simpson RN, Hollingsworth TJ, Jablonski MM. Enhanced Corneal Penetration of a Poorly Permeable Drug Using Bioadhesive Multiple Microemulsion Technology.Pharmaceutics. 2020 Jul 26;12(8). doi: 10.3390/pharmaceutics12080704. PubMed PMID: 32722550; PubMed Central PMCID: PMC7463957. 

View more references (pubmed link)

Jul 7, 2022