Whole Slide Imaging (WSI) System

The Whole Slide Imaging (WSI) System offers the ability to create a digital replica of the entire content of a glass microscope slide and to display and analyze this content on the computer, closely emulating traditional viewing of a slide with a conventional microscope. Virtual microscope slides are advantageous over digital photomicrographs because digitized slides can be moved in two dimensions and through multiple magnifications. 

 

Additionally, the technology to annotate digitized slides by overlay with arrows, lines, and text, compare immunohistochemistry and fluorescence microscopy side-by-side with an H&E stain, evaluate tissue microarrays, and perform computer assisted image analysis, further augments the utility of the system for research purposes.

Our center has capabilities to scan bright field slides (H&E, special stains, immunohistochemical stains) and fluorescent slides. The digital images can be analyzed with the use of multiple algorithms, such as positive pixel count, color colocalization, rare event detection, TMA lab, microvessel analysis, nuclear analysis, membrane analysis and Genie (Aperio Inc).