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Biorepository and Integrative Genomics (BIG) Initiative

Researchers at the UT Health Science Center (UTHSC) have partnered with doctors and scientists at Le Bonheur Children's Hospital and Regional One Hospital to establish the Biorepository and Integrative Genomics (BIG) Initiative – a collection of DNA samples to help doctors study the influence of genes, or blueprints in each of the body’s cells, on what diseases we get and how well we respond to treatment.  

The goal of the BIG Initiative is to facilitate research in Precision Medicine relevant to clinical care in underserved and disadvantaged communities across the state by developing resources to link and analyze genetic, health, and demographic data in these various populations. The BIG Initiative seeks to address the most-pressing health care needs in Tennessee, caring for vulnerable populations, eliminating health disparities, and engaging participating communities through innovative programs.

 

 

How Researchers Can Apply for BIG Data and/or Samples

To apply for samples and/or data, first identify a research cohort in the UTHSC research enterprise warehouse (rEDW) using TriNetX. Once a preliminary list of available samples in the cohort has been verified by and received from the IGB, then fill out a BIG Materials Distribution Request.

For more information, please read our BIG sample request FAQ.

Instructions to Complete Your Request

Once a preliminary list of available samples in the cohort has been verified by and received from the IGB, then fill out a BIG Materials Distribution Request using these instructions as needed.

 

Mar 1, 2024