Key Components of the Training Program

This residency program focuses on the following: (a) professional management of animal resources (b) medical and surgical management of laboratory animals to prevent and minimize adverse effects of spontaneous diseases on research results (c) selection of animal subjects and experimental methods on research protocols (d) independent and collaborative research (e) federal, state and local laws and regulations involving the use of animals in research (f) industry standard guidelines and performance based outcomes (g) Institutional Animal Care and Use Committee functions (h) biosafety and animal biosafety with emphasis in ABSL2 and ABSL3 husbandry, veterinary care, and operations.

Approximately 70% of the trainee’s time is devoted to clinical residency training in laboratory animal science and medicine consisting primarily of participation in clinical rotations, facility management, and teaching/training programs (AALAS Technician Training, research investigator training, and seminars on topics related to laboratory animal science and medicine). Courses are provided by the Department of Comparative Medicine include: Laboratory Animal Resources, Essentials of Animal Experimentation (CMED 711), and Biology and Pathophysiology of Lab Animals (CMED 712 & 713). The trainee gains clinical experience through interaction with the veterinarians on the training faculty, investigators, and technicians as problems are encountered and solved. Trainees are involved in all aspects of the clinical care program including: animal disease prevention and surveillance programs, environmental monitoring programs, experimental surgery and postoperative care, examination of animals and diagnosis of clinical problems (many of which are peculiar to the research environment), performing diagnostic tests as deemed useful and evaluating the results, selecting and carrying out therapeutic regimens in concert with the veterinary faculty and investigators as applicable, conducting gross and histological necropsy examinations and preparing necropsy reports, and communicating with investigators and the technical staff about animal health problems.

In addition, trainees routinely interact with the animal care staff, participate in staff meetings concerned with the management of the animal care resource, and assist with the review and periodic update of the standard operating procedures for the program of animal care. Another important aspect of the training program is the study of animal models for biomedical research; this information is conveyed via seminars and participation in the activities of the Institutional Animal Care and Use Committee including the review of animal study protocols and providing veterinary consultation to investigators using animal models. With the opening of the Regional Biocontainment Laboratory, trainees will receive basic and advance training in biosafety and animal biosafety that will prepare them for working in an ABSL3 facility.

Department of
Comparative Medicine

Chair: Timothy D. Mandrell, DVM, DACLAM

956 Court Avenue
Box 17, Room B106
Memphis, TN 38163
Phone: 901-448-5656
Fax: 901-448-8506