Pediatric Surgery

Ankush Gosain, MD, PhD, FACS, FAAP

faculty photo

Dr. Gosain received his Bachelor’s degree and the Provost’s Award for Research and Excellence from Johns Hopkins University in Baltimore, Maryland (1996).  He went on to receive an MD from Eastern Virginia Medical School in Norfolk, Virginia (2000).  Dr. Gosain started his General Surgery residency at Rosalind Franklin University of Medicine and Science, Mt. Sinai Hospital in Chicago (2000). During his residency, he completed an NIH Research Fellowship in Burns and Trauma at Loyola University Medical Center in Maywood, Illinois (2006) and received a PhD in Cell Biology, Neurobiology and Anatomy from Loyola University Chicago (2006).  He completed his General Surgery residency at Loyola University Medical Center in Maywood, Illinois (2008).  He then completed a Pediatric Surgery and Pediatric Surgical Oncology fellowships at University of Tennessee LeBonheur Children’s Medical Center and St. Jude Children’s Research Hospital in Memphis, Tennessee (2010).

Dr. Gosain’s first faculty appointment was as an Assistant Professor of Surgery, Pediatrics and Neuroscience at the University of Wisconsin-Madison (2010). Dr. Gosain founded and was the Director of the CHARM (Cloaca, Hirschsprung’s, AnoRectal Malformations) Clinic at the American Family Children’s Hospital. Additionally, he served as the Medical Director of the ACS-verified Pediatric Trauma Program, Surgical Director of the Pediatric Intensive Care Unit, Surgical Director of the Pediatric Oncology Program, and was a member of the Vascular Anomalies Team. While at the University of Wisconsin, he was selected for and completed the Physician Leadership Development Program.

Dr. Gosain was recruited to join the faculty of UTHSC/Le Bonheur Children’s Hospital in 2015. Dr. Gosain directs the Pediatric Surgery Research Laboratory at the Children’s Foundation Research Institute of Le Bonheur Children’s Hospital. His NIH-funded laboratory focuses on the development of the enteric nervous system and gastrointestinal mucosal immune system. The long-term goal of his research is to gain an understanding of the interactions between the enteric nervous and gastrointestinal immune systems in both development and disease to permit the generation of novel neuro-immunomodulatory therapies that may potentially target a broad range of congenital and acquired pediatric gastrointestinal tract diseases (Hirschsprung’s disease, necrotizing enterocolitis, intestinal atresia, motility disorders, inflammatory bowel disease, etc.).

Dr. Gosain’s clinical research focuses on optimizing modes of communication in pediatric surgery to ensure patient safety. This includes development of clinical pathways for common pediatric surgical conditions and pediatric trauma patients. Another area of active work is the utilization of a health information technology leveraged approach to improving provider communications during transitions of care for pediatric trauma patients in the hospital setting. Finally, Dr. Gosain is studying methods to optimize informed consent discussions in pediatric general surgery.

Dr. Gosain is certified by the American Board of Surgery in General Surgery and Pediatric Surgery. Dr. Gosain is actively involved in numerous national and international academic societies and has served as both an invited speaker as well as visiting professor based on his clinical and research expertise on multiple occasions.  He specializes in minimally-invasive surgery. His specific clinical interests are in Hirschsprung’s disease (congenital intestinal aganglionosis), anorectal malformations (imperforate anus, cloaca, cloacal exstrophy), oncology (hepatoblastoma, neuroblastoma, Wilms’ tumor, soft tissue sarcoma, rare tumors), and neonatal surgery (including esophageal atresia, intestinal atresias, congenital diaphragmatic hernia, congenital pulmonary malformations).

Research Interests

  • Enteric Nervous System Development
  • Mucosal Immune Development
  • Hirschsprung’s Disease and Hirschsprung’s-Associated Enterocolitis
  • Communication and Patient Safety
  • Pediatric Trauma and Wound Healing

Clinical Expertise

  • Hirschsprung’s disease
  • Anorectal malformations (Imperforate anus, cloaca, cloacal exstrophy)
  • Neonatal Surgery (Esophageal atresia, Congenital Diaphragmatic Hernia, Congenital Pulmonary Malformations)
  • Rare tumors (Hepatoblastoma, Peritoneal malignancies)
  • Pediatric Trauma and Burns

University and Hospital Appointments

  • Associate Professor of Surgery and Pediatrics, UTHSC
  • Affiliate Physician, St. Jude Children’s Research Hospital
  • Primary Investigator, Children’s Foundation Research Institute, Le Bonheur Children’s Hospital
  • Director, Pediatric Surgery Clinical Research

Medical School

Eastern Virginia Medical School, Norfolk, VA

Post Graduate Training

Residency: Rosalind Franklin University of Medicine and Science, Chicago Medical School, Mt. Sinai Hospital, Chicago, IL

Residency: Loyola University Medical Center, Maywood, IL

Fellowship: Pediatric Surgery and Pediatric Surgical Oncology, Le Bonheur Children’s Medical Center and St. Jude Children’s Research Hospital, Memphis, TN

Research Fellowship: NIH Research Fellowship in Burns and Trauma, Burn and Shock Trauma Institute, Loyola University Medical Center, Maywood, IL

PhD: Ph.D., Cell Biology, Neurobiology & Anatomy, Loyola University Chicago, Chicago, IL

Professional: Physician Leadership Development Program, University of Wisconsin-Madison, Madison, WI

Board Certifications and Certificates

  • American Board of Surgery, General Surgery
  • American Board of Surgery, Pediatric Surgery
  • Advanced Trauma Life Support, Instructor
  • Advanced Trauma Life Support, Course Director

Recent Publications

  • Desai N, Veras LV, Gosain A. Using bibliometrics to analyze the state of academic productivity in US pediatric surgery training programs. J Pediatr Surg. 2018 Mar 5. pii: S0022-3468(18)30148-9. doi: 10.1016/j.jpedsurg.2018.02.063. [Epub ahead of print] PubMed PMID: 29580787.
  • Johnson CD, Barlow-Anacker AJ, Pierre JF, Touw K, Erickson CS, Furness JB, Epstein ML, Gosain A. Deletion of choline acetyltransferase in enteric neurons results in postnatal intestinal dysmotility and dysbiosis. FASEB J. 2018 Mar 23:fj201701474RR. doi: 10.1096/fj.201701474RR. [Epub ahead of print] PubMed PMID: 29570391.
  • Cameron DB, Williams R, Geng Y, Gosain A, Arnold MA, Guner YS, Blakely ML, Downard CD, Goldin AB, Grabowski J, Lal DR, Dasgupta R, Baird R, Gates RL, Shelton J, Jancelewicz T, Rangel SJ, Austin MT. Time to appendectomy for acute appendicitis: A systematic review. J Pediatr Surg. 2018 Mar;53(3):396-405. doi: 10.1016/j.jpedsurg.2017.11.042. Epub 2017 Nov 20. Review. PubMed PMID: 29241958.
  • Dasgupta R, Renaud E, Goldin AB, Baird R, Cameron DB, Arnold MA, Diefenbach KA, Gosain A, Grabowski J, Guner YS, Jancelewicz T, Kawaguchi A, Lal DR, Oyetunji TA, Ricca RL, Shelton J, Somme S, Williams RF, Downard CD. Ovarian torsion in pediatric and adolescent patients: A systematic review. J Pediatr Surg. 2017 Nov 16. pii: S0022-3468(17)30709-1. doi: 10.1016/j.jpedsurg.2017.10.053. [Epub ahead of print] PubMed PMID: 29153467.
  • El-Gohary Y, Abdelhafeez A, Paton E, Gosain A, Murphy AJ. Pyloric stenosis: an enigma more than a century after the first successful treatment. Pediatr Surg Int. 2018 Jan;34(1):21-27. doi: 10.1007/s00383-017-4196-y. Epub 2017 Oct 13. Review. PubMed PMID: 29030700.
  • Odom EB, Janis JE, Gosain A, Barker JC, Buck DW 2nd. Education for the Future: What the Residents Want. Plast Reconstr Surg. 2017 Oct;140(4):646e-647e. doi: 10.1097/PRS.0000000000003741. PubMed PMID: 28953756.

View more references (pubmed link)