Pediatric Surgery


Ankush Gosain, MD, PhD, FACS, FAAP

faculty photo

Dr. Gosain received his Bachelor’s degree and the Provost’s Award for Research and Excellence from Johns Hopkins University in Baltimore, Maryland (1996).  He went on to receive an MD from Eastern Virginia Medical School in Norfolk, Virginia (2000).  Dr. Gosain started his General Surgery residency at Rosalind Franklin University of Medicine and Science, Mt. Sinai Hospital in Chicago (2000). During his residency, he completed an NIH Research Fellowship in Burns and Trauma at Loyola University Medical Center in Maywood, Illinois (2006) and received a PhD in Cell Biology, Neurobiology and Anatomy from Loyola University Chicago (2006).  He completed his General Surgery residency at Loyola University Medical Center in Maywood, Illinois (2008).  He then completed a Pediatric Surgery and Pediatric Surgical Oncology fellowships at University of Tennessee LeBonheur Children’s Medical Center and St. Jude Children’s Research Hospital in Memphis, Tennessee (2010).

Dr. Gosain’s first faculty appointment was as an Assistant Professor of Surgery, Pediatrics and Neuroscience at the University of Wisconsin-Madison (2010). Dr. Gosain founded and was the Director of the CHARM (Cloaca, Hirschsprung’s, AnoRectal Malformations) Clinic at the American Family Children’s Hospital. Additionally, he served as the Medical Director of the ACS-verified Pediatric Trauma Program, Surgical Director of the Pediatric Intensive Care Unit, Surgical Director of the Pediatric Oncology Program, and was a member of the Vascular Anomalies Team. While at the University of Wisconsin, he was selected for and completed the Physician Leadership Development Program.

Dr. Gosain was recruited to join the faculty of UTHSC/Le Bonheur Children’s Hospital in 2015. Dr. Gosain directs the Pediatric Surgery Research Laboratory at the Children’s Foundation Research Institute of Le Bonheur Children’s Hospital. His NIH-funded laboratory focuses on the development of the enteric nervous system and gastrointestinal mucosal immune system. The long-term goal of his research is to gain an understanding of the interactions between the enteric nervous and gastrointestinal immune systems in both development and disease to permit the generation of novel neuro-immunomodulatory therapies that may potentially target a broad range of congenital and acquired pediatric gastrointestinal tract diseases (Hirschsprung’s disease, necrotizing enterocolitis, intestinal atresia, motility disorders, inflammatory bowel disease, etc.).

Dr. Gosain’s clinical research focuses on optimizing modes of communication in pediatric surgery to ensure patient safety. This includes development of clinical pathways for common pediatric surgical conditions and pediatric trauma patients. Another area of active work is the utilization of a health information technology leveraged approach to improving provider communications during transitions of care for pediatric trauma patients in the hospital setting. Finally, Dr. Gosain is studying methods to optimize informed consent discussions in pediatric general surgery.

Dr. Gosain is certified by the American Board of Surgery in General Surgery and Pediatric Surgery. Dr. Gosain is actively involved in numerous national and international academic societies and has served as both an invited speaker as well as visiting professor based on his clinical and research expertise on multiple occasions.  He specializes in minimally-invasive surgery. His specific clinical interests are in Hirschsprung’s disease (congenital intestinal aganglionosis), anorectal malformations (imperforate anus, cloaca, cloacal exstrophy), oncology (hepatoblastoma, neuroblastoma, Wilms’ tumor, soft tissue sarcoma, rare tumors), and neonatal surgery (including esophageal atresia, intestinal atresias, congenital diaphragmatic hernia, congenital pulmonary malformations).

Research Interests

  • Enteric Nervous System Development
  • Mucosal Immune Development
  • Hirschsprung’s Disease and Hirschsprung’s-Associated Enterocolitis
  • Communication and Patient Safety
  • Pediatric Trauma and Wound Healing

Clinical Expertise

  • Hirschsprung’s disease
  • Anorectal malformations (Imperforate anus, cloaca, cloacal exstrophy)
  • Neonatal Surgery (Esophageal atresia, Congenital Diaphragmatic Hernia, Congenital Pulmonary Malformations)
  • Rare tumors (Hepatoblastoma, Peritoneal malignancies)
  • Pediatric Trauma and Burns

University and Hospital Appointments

  • Associate Professor of Surgery and Pediatrics, UTHSC
  • Affiliate Physician, St. Jude Children’s Research Hospital
  • Primary Investigator, Children’s Foundation Research Institute, Le Bonheur Children’s Hospital
  • Director, Pediatric Surgery Clinical Research

Medical School

Eastern Virginia Medical School, Norfolk, VA

Post Graduate Training

Residency: Rosalind Franklin University of Medicine and Science, Chicago Medical School, Mt. Sinai Hospital, Chicago, IL

Residency: Loyola University Medical Center, Maywood, IL

Fellowship: Pediatric Surgery and Pediatric Surgical Oncology, Le Bonheur Children’s Medical Center and St. Jude Children’s Research Hospital, Memphis, TN

Research Fellowship: NIH Research Fellowship in Burns and Trauma, Burn and Shock Trauma Institute, Loyola University Medical Center, Maywood, IL

PhD: Ph.D., Cell Biology, Neurobiology & Anatomy, Loyola University Chicago, Chicago, IL

Professional: Physician Leadership Development Program, University of Wisconsin-Madison, Madison, WI

Board Certifications and Certificates

  • American Board of Surgery, General Surgery
  • American Board of Surgery, Pediatric Surgery
  • Advanced Trauma Life Support, Instructor
  • Advanced Trauma Life Support, Course Director

Recent Publications

  • Gosain A. What's New in Critical Illness and Injury Science? Case reports: The first step on a path toward cure. Int J Crit Illn Inj Sci. 2018 Apr-Jun;8(2):55-56. doi: 10.4103/2229-5151.234585. PubMed PMID: 29963406; PubMed Central PMCID: PMC6018259.
  • Goldstein AM, Blair AB, Keswani SG, Gosain A, Morowitz M, Kuo J, Levine M, Ahuja N, Hackam DJ; Basic Science Committee of the Society of University Surgeons. A Roadmap for Aspiring Surgeon-Scientists in Today's Healthcare Environment. Ann Surg. 2018 Jun 28. doi: 10.1097/SLA.0000000000002840. [Epub ahead of print] PubMed PMID: 29958227.
  • Desai N, Veras L, Gosain A. Using Bradford's law of scattering to identify the core journals of pediatric surgery. J Surg Res. 2018 Sep;229:90-95. doi: 10.1016/j.jss.2018.03.062. Epub 2018 Apr 17. PubMed PMID: 29937022.
  • Veras LV, Chotai PN, Tumen AZ, Gosain A. Impaired growth outcomes in children with congenital colorectal diseases. J Surg Res. 2018 Sep;229:102-107. doi: 10.1016/j.jss.2018.03.069. Epub 2018 Apr 23. PubMed PMID: 29936975; PubMed Central PMCID: PMC6020164.
  • Lucas DJ, Gosain A. Association of Comorbidities With Adverse Outcomes After Enterostomy Closure in Premature Neonates. JAMA Surg. 2018 May 16. doi: 10.1001/jamasurg.2018.0880. [Epub ahead of print] PubMed PMID: 29799909.
  • Jancelewicz T, Brindle ME, Harting MT, Tolley EA, Langham MR Jr, Lally PA, Gosain A, Storgion SA, Kays DW; Congenital Diaphragmatic Hernia Study Group. Extracorporeal Membrane Oxygenation (ECMO) Risk Stratification in Newborns with Congenital Diaphragmatic Hernia (CDH). J Pediatr Surg. 2018 Apr 14. pii: S0022-3468(18)30254-9. doi: 10.1016/j.jpedsurg.2018.04.014. [Epub ahead of print] PubMed PMID: 29754878.

View more references (pubmed link)