Proteomics and Metabolomics (PMC)
The PMC Core's mission is to provide the UTHSC community with state-ofthe-artmass spectral technology and support to facilitate molecular-level discoveries that transform and advance our understanding of biological systems to solve challenging, relevant scientific questions in the life sciences.
Introduction & Services
The Proteomics and Metabolomics Core (PMC) was established through the Office of the Vice Chancellor for Research in 2015. The Core was created to provide resources for the highest quality mass spectrometry-based analysis supporting research needs in the fields of proteomics and metabolomics. The Core provides consultations to optimize experiment design and to interpret generated data. Services include identification andnabsolute or differential quantification of metabolites, drugs, and other small molecules in body fluids, cell and tissue extracts, identification of individual proteins in simple and highly complex protein mixtures, identification and mapping of posttranslational and other modifications of proteins, differential protein expression analysis based on precursor ion quantification (SILAC, dimethyl labelling), reporter ion quantification (iTRAQ/TMT labelling), and precursor ion area detection (label-free analysis), analysis of protein-protein interactions, and determination of the molecular masses of analytes.