Case 001: 76-Year-Old White Male with Plaque on the Left Cheek
Contributed by Andre Thompson, M.D. and Jian-Ping Cai M.D. under the supervision of Andrzej Slominski, M.D., Ph.D.
A 76-year-old white male with slow-growing, indurated, flesh-colored, and slightly depressed plaque on the left cheek.
(Click a photo to view a larger image.)
Image (1) Sun-damaged skin (solar elastosis on the left side) with atrophic epidermis, fibrosis in the papillary and superficial reticular dermis, micronodular inflammatory infiltrate, and diffuse proliferation of spindle cells in deep reticular dermis.
- Desmoplastic melanoma
Comment: Immunohistochemical staining showed that neoplastic cells were positive for S-100 and negative for Keratin.
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