FOR IMMEDIATE RELEASE
For more information contact:
Beverly Goodwin Sousoulas
UTHSC Preventive Medicine
Anne W. Manning
UTHSC Communications and Marketing
Innovative Smoking Cessation Research Study Moves from
Mayo Clinic to
Memphis, Tennessee (July 20, 2006)--Researchers at
the University of Tennessee Health Science Center (UTHSC) Department of
Preventive Medicine are looking for 275 smokers to participate in a new
approach to smoking cessation called Step. A total of 400 adult smokers
will be enrolled in the study. The study commenced at Mayo Clinic in
Cigarette smokers who are 18 years of age or older, in relatively good health, who self-report smoking at least 10 cigarettes each day, and who are willing to accept random assignment are eligible to participate. Participants must agree to commit to the study for at least 24 months following screening. One of the major problems in achieving long-term behavior change with smoking cessation is that smoking relapse rates are alarmingly high. Of those who make a serious attempt to quit, over half (58%) have resumed smoking within a two-week period.
The current study will investigate what is a common medical approach to treatment, namely a “stepped care” approach to smoking cessation. There will be two different comparisons in this study. Both comparisons start with an effective behavioral stop-smoking program. All participants will also be given the nicotine patch at no charge to help them quit. After six months, if participants have either not quit smoking or have relapsed, participants in one condition will get the interventions repeated while in the other, they will receive more aggressive behavioral and pharmacologic intervention (i.e., four sessions of behavioral counseling and bupropion). After 12 months, participants who are still smoking, depending on the group they are randomly assigned to, will again either have the intervention repeated or get a more intensive intervention (six sessions of behavioral intervention, plus the patch, plus nicotine chewing gum). It is important to note that all participants, regardless of the group they are assigned to, get an effective stop-smoking program plus free pharmacologic intervention for smoking cessation.
The principal investigator for the study at UTHSC is
Robert C. Klesges. PhD. Dr. Klesges has
a 20-year history of conducting important clinical trials for smoking cessation
and obesity in
Anyone interested in participating in the Step research study should call the UTHSC Preventive Medicine recruitment department at 901-448-8400 or 1-800-916-2606 to determine eligibility.
As the flagship statewide academic health system, the
University of Tennessee Health Science Center is focused on a four-tier mission
of education, research, patient care and community service, all in support of a
single goal: to improve the health of Tennesseans. Offering a broad range of
postgraduate training opportunities, the main campus, with its six colleges, is
This study quantifies the economic impact of the UTHSC on the economy of the state of Tennessee for FY2010.
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