Lindsay Schwarz, PhD


Lindsay Schwarz


Assistant Member

Developmental Neurobiology
St. Jude Children's Research Hospital
Affiliated Assistant Professor
Department of Anatomy and Neurobiology

Developmental Neurobiology
MS 323, Room D2025F
St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Phone: (901) 595-2830
Email: Lindsay Schwarz

Education

  • PhD Institution: University of CA, San Diego
  • Postdoctoral: Stanford University

Links

Research Interests

  • Mechanisms regulating diverse functions of neuromodulatory circuits
  • Activity patterns of neuromodulatory neurons in vivo during arousal-related behaviors
  • Molecular diversity of locus coeruleus neurons
  • How changes in neuromodulatory circuits promote psychiatric and neurodegenerative disorders

Representative Publications

  • Yackle K, Schwarz LA, Kam K, Sorokin JM, Huguenard JR, Feldman JL, Luo L, Krasnow MA. Breathing control center neurons that promote arousal in mice. Science. 2017 Mar 31;355(6332):1411-1415. doi: 10.1126/science.aai7984. Epub 2017 Mar 30. PubMed PMID: 28360327; PubMed Central PMCID: PMC5505554.
  • Huang WH, Guenthner CJ, Xu J, Nguyen T, Schwarz LA, Wilkinson AW, Gozani O, Chang HY, Shamloo M, Luo L. Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome. Neuron. 2016 Oct 19;92(2):392-406. doi: 10.1016/j.neuron.2016.09.019. Epub 2016 Sep 29. PubMed PMID: 27693255; PubMed Central PMCID: PMC5098476.
  • Gong H, Xu D, Yuan J, Li X, Guo C, Peng J, Li Y, Schwarz LA, Li A, Hu B, Xiong B, Sun Q, Zhang Y, Liu J, Zhong Q, Xu T, Zeng S, Luo Q. High-throughput dual-colour precision imaging for brain-wide connectome with cytoarchitectonic landmarks at the cellular level. Nat Commun. 2016 Jul 4;7:12142. doi: 10.1038/ncomms12142. PubMed PMID: 27374071; PubMed Central PMCID: PMC4932192.
  • Schwarz LA, Miyamichi K, Gao XJ, Beier KT, Weissbourd B, DeLoach KE, Ren J, Ibanes S, Malenka RC, Kremer EJ, Luo L. Viral-genetic tracing of the input-output organization of a central noradrenaline circuit. Nature. 2015 Aug 6;524(7563):88-92. doi: 10.1038/nature14600. Epub 2015 Jul 1. PubMed PMID: 26131933; PubMed Central PMCID: PMC4587569.
  • Scudder SL, Goo MS, Cartier AE, Molteni A, Schwarz LA, Wright R, Patrick GN. Synaptic strength is bidirectionally controlled by opposing activity-dependent regulation of Nedd4-1 and USP8. J Neurosci. 2014 Dec 10;34(50):16637-49. doi: 10.1523/JNEUROSCI.2452-14.2014. PubMed PMID: 25505317; PubMed Central PMCID: PMC4261092.
  • Schwarz LA, Patrick GN. Ubiquitin-dependent endocytosis, trafficking and turnover of neuronal membrane proteins. Mol Cell Neurosci. 2012 Mar;49(3):387-93. doi: 10.1016/j.mcn.2011.08.006. Epub 2011 Aug 22. Review. PubMed PMID: 21884797; PubMed Central PMCID: PMC3279607.

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