Catherine Kaczorowski, Ph.D.

Catherine Kaczorowski, Ph.D.

Assistant Professor
Department of Anatomy and Neurobiology

The University of Tennessee Health Science Center
855 Monroe Avenue, Suite 515
Memphis, TN 38163
Tel: (901) 448-2178
Fax: (901) 448-7193
Labs: 228 Wittenborg Anatomy Building
Office: 231 A Wittenborg Anatomy Building
Email: Catherine Kaczorowski

Spotlight Interview

American Federation for Aging Research


  • Ph.D. Institution: Northwestern University, Neuroscience
  • Postdoctoral: Medical College of Wisconsin and University of Wisconsin-Milwaukee, Physiology and Bioengineering & Biotechnology


To identify early causative events that underlie cognitive deficits associated with 'normal' aging and Alzheimer's disease. Using multidisciplinary approaches that combine innovative high resolution and high throughput membrane proteomics, transcriptomics, viral-based gene transduction approaches, behavioral assays, and electrophysiology, our research aims to understand how misregulated membrane proteins in the hippocampus of aging and AD mouse models alter hippocampal neuron excitability and memory. Our goal is to transform basic discoveries into treatments that prevent and cure dementias in aging.

Representative Publications

  • Neuner SM, Ding S, Kaczorowski CC. Knockdown of heterochromatin protein 1 binding protein 3 recapitulates phenotypic, cellular, and molecular features of aging. Aging Cell. 2018 Dec 13:e12886. doi: 10.1111/acel.12886. [Epub ahead of print] PubMed PMID: 30549219.
  • Neuner SM, Wilmott LA, Hope KA, Hoffmann B, Chong JA, Abramowitz J, Birnbaumer L, O'Connell K, Tryba AK, Greene AS, Chan CS, Kaczorowski CC. Corrigendum to "TRPC3 channels critically regulate hippocampal excitability and contextual fear memory" Behav. Brain Res. 281(March) 2015, 69-77. Behav Brain Res. 2017 Aug 14;332:379. doi: 10.1016/j.bbr.2017.05.038. Epub 2017 May 30. PubMed PMID: 28576459.
  • Neuner SM, Wilmott LA, Burger C, Kaczorowski CC. Advances at the intersection of normal brain aging and Alzheimer's disease. Behav Brain Res. 2017 Mar 30;322(Pt B):187-190. doi: 10.1016/j.bbr.2017.01.052. PubMed PMID: 28231898.
  • Garfinkel BP, Arad S, Neuner SM, Netser S, Wagner S, Kaczorowski CC, Rosen CJ, Gal M, Soreq H, Orly J. HP1BP3 expression determines maternal behavior and offspring survival. Genes Brain Behav. 2016 Sep;15(7):678-88. doi: 10.1111/gbb.12312. PubMed PMID: 27470444.
  • Neuner SM, Garfinkel BP, Wilmott LA, Ignatowska-Jankowska BM, Citri A, Orly J, Lu L, Overall RW, Mulligan MK, Kempermann G, Williams RW, O'Connell KM, Kaczorowski CC. Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging. Neurobiol Aging. 2016 Oct;46:58-67. doi: 10.1016/j.neurobiolaging.2016.06.008. Epub 2016 Jun 17. PubMed PMID: 27460150; PubMed Central PMCID: PMC5018442.
  • Neuner SM, Wilmott LA, Hoffmann BR, Mozhui K, Kaczorowski CC. Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models. Behav Brain Res. 2017 Mar 30;322(Pt B):288-298. doi: 10.1016/j.bbr.2016.06.002. Epub 2016 Jun 2. PubMed PMID: 27265785; PubMed Central PMCID: PMC5135662.

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