Byron C. Jones, Ph.D.

 

Professor

Genetics, Genomics & Informatics
The University of Tennessee
Health Science Center

The University of Tennessee Health Science Center
321 Wittenborg Anatomy Building
Memphis, TN 38163
Phone: (901) 448-2814
Email: Byron C. Jones


Education

  • Ph.D. Psychology, University of Arizona
  • Postdoctoral training 1975-76 - University of Arizona with Henry Yamamura
  • Postdoctoral training, 1986-89 - Alcohol Research Center, University of Colorado with V. Gene Erwin
  • Taught and conducted research at The Pennsylvania State University 1991 - 2014.

Research Interests

Genetics of adaptation to stress relative to consumption of alcohol and function of the HPA axis. My research group is interested in individual differences in response to chronic stressful events in terms of changes in alcohol consumption and hypothalamus-pituitary-adrenal axis function. Through the use of genetically defined animals, we can identify candidate genes and biochemical pathways that underlie these forms of adaptation.

Toxicogenetics of pesticides and neurotoxins. The primary interest here is in the genetic basis of individual differences in susceptibility to neurological damage (related to Parkinson's disease) produced by exposure to pesticides and herbicides. Our aim here is to model the pathophysiology related to Parkinson's disease in genetically defined mice and to relate what we find in mice to understanding why some individuals are more susceptible to pesticide-induced neurodegeneration than others.

Genetics of metal regulation in the brain. Iron, copper and zinc are necessary elements for the development and function of the brain. Too much or too little of these elements have deleterious effects on brain function and thus must be tightly regulated. Our aim is to discover the genes and gene networks that underlie individual differences in the regulation of these important metals.