Current Clinical Research and Product Trials
Fluoride Varnish Application for Treatment of White Spot Lesion After Fixed Orthodontic Treatment. A Pilot Study
- PI: Dr. Franklin Garcia-Godoy and Dr. Terry Trojan
- To determine the efficacy of fluoride varnish (5% sodium fluoride with tricalcium phosphate) in reverting white spot lesions (WSLs) after fixed orthodontic treatment as compared to fluoride gel (1.23% APF).
- Enrollment: Open to Patients in the UTHSC Orthodontic Clinic
- Please contact 901-448-2210 for more information.
Effects of Non-Thermal Plasma Treatment on Composite Restoration and Caries Prevention.
- PI: Dr. Liang Hong
- Purpose: To investigate the effects of an investigative non-thermal plasma brush on composite restorations and caries prevention.
- Enrollment: Open to patients in the UTHSC dental clinics.
- Please contact 901-448-1963 for more information.
Influence of Maternal Factors on Caries Development in Early Childhood - A CANDLE Ancillary Study

- PIs: Dr. Franklin Garcia-Godoy, Dr. Liang Hong
- Co-I: Dr. Fran Tylavsky
- Purpose: Assessment of the role maternal factors play in the development of dental caries in early childhood.
- Enrollment: CANDLE study participants only
- Current Participants: please direct any questions to Laurie at 901-448-2210.
A Clinical Evaluation of NobelProcera ™ Implant Bar Overdenture in the Mandible or Maxilla on 4 NobelReplace ™ CC Implants
- PI: Dr. David Cagna
- Purpose: To determine the bone behavior and survival rates of the NobelProcera TM implants, the bar, and the overdenture by evaluating its clinical behavior.
- Enrollment: Open to qualified patients in the Department of Prosthodontics
- Please contact Dr. Cagna for more information: 901-448-6930.
Multi-Center Phase 3 Trial of Minocycline HCl 1mg Microsphere for the Use in Subjects with Peri-Implantitis: Clinical and Microbiological Evaluations
- PI: Dr. Paul Bland
- Purpose: To evaluate the safety, effectiveness, and antimicrobial effect of an investigational drug, Minocycline HCl Microspheres 1mg, on peri-implantitis following mechanical debridement as compared to mechanical debridement alone.
- Enrollment: Open to qualified patients in the Department of Periodontics
- ? Please contact 901-448-2210 for more information.
